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Article

Characterization of glucagon-like peptide-1 receptor-binding determinants.

Journal of molecular endocrinology - 1 Dec 2000

Xiao Q, Jeng W, Wheeler M B

Abstract excerpt

Glucagon-like peptide 1 (GLP-1) is a potent insulinotropic hormone currently under study as a therapeutic agent for type 2 diabetes. Since an understanding of the molecular mechanisms leading to high-affinity receptor (R) binding and activation may facilitate the development of more potent GLP-1R agonists, we have localized specific regions of GLP-1R required for binding. The purified N-terminal fragment...

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Source

Identifiers

PMID: 11116211
DOI: 10.1677/jme.0.0250321

Genes

GIP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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