Article
Confirmation of the DRB1-DQB1 loci as the major component of IDDM1 in the isolated founder population of Sardinia.
Human molecular genetics - 12 Dec 2000
Zavattari P, Lampis R, Mulargia A, Loddo M, Angius E, Todd J A, Cucca F
Abstract excerpt
There is considerable uncertainty and debate concerning the application of linkage disequilibrium (LD) mapping in common multifactorial diseases, including the choice of population and the density of the marker map. Previously, it has been shown that, in the large cosmopolitan population of the UK, the established type 1 diabetes IDDM1 locus in the HLA region could be mapped with high resolution by LD. The LD...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
