Article
[Molecular analysis of the LDL receptor].
Nihon rinsho. Japanese journal of clinical medicine - 1 Dec 1994
Yokode M, Kita T
Abstract excerpt
The LDL receptor is a cell surface glycoprotein that regulates plasma cholesterol by mediating endocytosis of LDL, the major cholesterol transport protein in human plasma. Mutations in the LDL receptor gene cause familial hypercholesterolemia (FH). The LDL receptor was purified in 1982, its cDNA...
Topics
- Animals
- Base Sequence
- Cholesterol
- Homeostasis
- Humans
- Hyperlipoproteinemia Type II
- Liver
- Molecular Sequence Data
- Mutation
- Receptors, LDL