Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular pathology of familial hypercholesterolemia, related dyslipidemias and therapies beyond the statins.

Critical reviews in clinical laboratory sciences - 1 Jan 2000

Faiz Fathimath, Hooper Amanda J, van Bockxmeer Frank M

Abstract excerpt

The development of the statin class of cholesterol-lowering drugs is one of the most significant success stories of modern pharmacotherapy. World-wide there are an estimated 150 million people on statins, with the emerging economies of India and China predicted to contribute significantly to that number. Notwithstanding their success, a significant number of people cannot tolerate statins because of serious side...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dyslipidemias
Share to LDLR gene
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hydroxymethylglutaryl-CoA Reductase Inhibitors

Share to Hyperlipoproteinemia Type II

Share to Receptors, LDL

Share to RNA Splice Sites

Source

Identifiers

PMID: 22214202
DOI: 10.3109/10408363.2011.646942

Genes

LDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular pathology of familial hypercholesterolemia, related dyslipidemias and therapies beyond the statins.PMID 22214202Read ↗

Molecular aspects of hypercholesterolemia treatment: current perspectives and hopes.Semantic proximity Read ↗

From physiopathology to treatment of familial hypercholesterolemia: Existing and emerging pharmacotherapies.Semantic proximity Read ↗

What is new in familial hypercholesterolemia?Semantic proximity Read ↗

Genetic and molecular architecture of familial hypercholesterolemia.Semantic proximity Read ↗

Familial Hypercholesterolemia: Update and Review.Semantic proximity Read ↗

Familial Hypercholesterolemia: The Most Frequent Cholesterol Metabolism Disorder Caused DiseaseSemantic proximity Read ↗

Lipoprotein metabolism in familial hypercholesterolemiaSemantic proximity Read ↗

Genetic determinants of inherited susceptibility to hypercholesterolemia - a comprehensive literature review.Semantic proximity Read ↗

New Approaches in Detection and Treatment of Familial Hypercholesterolemia.Semantic proximity Read ↗

[Advances in diagnosis and treatment of familial hypercholesterolemia].Semantic proximity Read ↗

Familial hypercholesterolemia.Semantic proximity Read ↗

Molecular basis of familial hypercholesterolemiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.