Article
Biologic role(s) of the 25(R),26-hydroxycholesterol metabolic pathway.
Biochimica et biophysica acta - 15 Dec 2000
Javitt N B
Abstract excerpt
Expression of the gene coding for the synthesis of 25(R), 26-hydroxycholesterol in many tissues and the finding that this sterol can be the sole pathway for the production of bile acids have led to a renewed interest in this metabolic pathway. A further impetus for exploring the normal biologic roles that are served by expression of the CYP27A1 gene is the knowledge that mutations in humans are associated with...
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