Article
Cytochrome P450-mediated metabolism of vitamin D.
Journal of lipid research - 1 Jan 2014
Jones Glenville, Prosser David E, Kaufmann Martin
Abstract excerpt
The vitamin D signal transduction system involves a series of cytochrome P450-containing sterol hydroxylases to generate and degrade the active hormone, 1α,25-dihydroxyvitamin D3, which serves as a ligand for the vitamin D receptor-mediated transcriptional gene expression described in companion articles in this review series. This review updates our current knowledge of the specific anabolic cytochrome P450s...
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