Article
Multigenerational cortical inheritance of the Rax2 protein in orienting polarity and division in yeast.
Science (New York, N.Y.) - 8 Dec 2000
Chen T, Hiroko T, Chaudhuri A, Inose F, Lord M, Tanaka S, Chant J, Fujita A
Abstract excerpt
Diploid yeast cells repeatedly polarize and bud from their poles, probably because of highly stable marks of unknown composition. Here, Rax2, a membrane protein, was shown to behave as such a mark. The Rax2 protein itself was inherited immutably at the cell cortex for multiple generations, and Rax2 was shown to have a half-life exceeding several generations. The persistent inheritance of cortical protein markers...
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