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Article

Molecular evidence for multicentric development of thyroid carcinomas in patients with familial adenomatous polyposis.

The American journal of pathology - 1 Dec 2000

Miyaki M, Iijima T, Ishii R, Hishima T, Mori T, Yoshinaga K, Takami H, Kuroki T, Iwama T

Abstract excerpt

Familial adenomatous polyposis is characterized by multiple colorectal adenomas and an increased incidence of colorectal carcinomas. Patients also develop various extracolonic tumors, of which, thyroid carcinoma is common in young females. The occurrence of multiple carcinomas in one thyroid is frequently observed, although some carcinomas are solitary. To clarify whether each carcinoma develops independently or...

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Identifiers

PMID: 11106555
DOI: 10.1016/S0002-9440(10)64821-3
PMCID: PMC1885783

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APC

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Source receipt: pubmed, retrieved 7 Sept 2026.

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