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Article

Mutational Analysis of the <i>APC</i> Gene in Cribriform‐Morula Variant of Papillary Thyroid Carcinoma

17 Apr 2006

Abstract excerpt

INTRODUCTION: Familial adenomatous polyposis (FAP) is an inherited autosomal dominant syndrome caused by germline mutations in the adenomatous polyposis coli (APC) gene. Papillary thyroid cancer is one of the extracolonic manifestations of FAP. A characteristic histologic feature of this type of thyroid tumor is the cribriform-morula variant of papillary thyroid carcinoma (CMVPTC). METHODS: To investigate roles...

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PMID: 16680592
DOI: 10.1007/s00268-005-0368-3

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