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Article

BRCA1 and BRCA2 mutations in breast cancer families with multiple primary cancers.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Nov 2000

Shih H A, Nathanson K L, Seal S, Collins N, Stratton M R, Rebbeck T R, Weber B L

Abstract excerpt

Ninety-eight women ascertained from high-risk breast/ovarian cancer clinics with breast cancer reporting at least one other primary cancer in themselves or in a relative with breast cancer were compared with 99 women with breast cancer who reported a family history of breast cancer only. All DNA was screened for coding region mutations in BRCA1 and BRCA2 using heteroduplex analysis, followed by direct sequencing....

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Source

Identifiers

PMID: 11106241

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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