Article
BRCA2 germline mutations in primary cancer of the fallopian tube.
Oncology reports - 1 Aug 2004
Casarsa Sara, Puglisi Fabio, Baudi Francesco, De Paola Loredana, Venuta Salvatore, Piga Andrea, Di Loreto Carla, Marchesoni Diego, D'Elia Angela Valentina, Damante Giuseppe
Abstract excerpt
Germline mutations of BRCA1 and BRCA2 genes confer susceptibility to breast and ovarian cancer. It has been recently reported that BRCA1/2 mutations may also predispose to fallopian tube cancer. We report the presence of germline BRCA2 gene mutations in three out of four subjects with fallopian tube cancer diagnosed in a two-year time span at our clinic. The mothers of two of these women suffered from breast or...
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