Article
Pathogenesis of Helicobacter pylori infection.
Helicobacter - 1 Oct 2008
Torres Javier, Backert Steffen
Abstract excerpt
The clinical outcome of Helicobacter pylori infection is determined by a complex scenario of interactions between the bacterium and the host. The main bacterial factors associated with colonization and pathogenicity comprise outer membrane proteins including BabA, SabA, OipA, AlpA/B, as well as the virulence factors CagA in the cag pathogenicity island (cagPAI) and the vacuolating cytotoxin VacA. The multitude of...
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