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Article

Major virulence factors, VacA and CagA, are commonly positive in <i>Helicobacter pylori</i> isolates in Japan

1 Mar 1998

Abstract excerpt

BACKGROUND: VacA and CagA proteins have been reported to be major virulence factors of Helicobacter pylori. However, antibodies against these proteins are frequently found in the sera of Japanese patients regardless of their gastroduodenal status. AIM: To evaluate the expression of VacA and CagA proteins by H pylori strains isolated in Japan. METHODS: By using specific antibodies raised against recombinant VacA...

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PMID: 9577338
DOI: 10.1136/gut.42.3.338

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