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Article

A cancer modifier role for parathyroid hormone-related protein.

Oncogene - 9 Nov 2000

Manenti G, Peissel B, Gariboldi M, Falvella F S, Zaffaroni D, Allaria B, Pazzaglia S, Rebessi S, Covelli V, Saran A, Dragani T A

Abstract excerpt

The parathyroid hormone-related protein (PTHrP) gene (Pthlh) maps in the distal region of mouse chromosome 6 that contains a quantitative trait locus associated with genetic predisposition to skin tumorigenesis. Here, we report a genetic polymorphism located in the osteostatin encoding region of the Pthlh gene and that produces Thr/ Pro PTHrP variants. PthlhThr and PthlhPro alleles were significantly linked with...

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Identifiers

PMID: 11103933
DOI: 10.1038/sj.onc.1203916

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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