Article
A new study challenges the current belief of a high human male:female mutation ratio.
Trends in genetics : TIG - 1 Dec 2000
Crow J F
Abstract excerpt
A recent comparison of a DNA region that was transposed from the X to the Y chromosome 3-4 million years ago, with the same region on the X chromosome showed only a slight excess of mutant changes on the Y chromosome. This translates to an estimate of 1.7 for the ratio of the male to female mutation rate, much less than the average 5.1 of previous studies. The authors argue that this throws doubt not only on...
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