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Article

Self-association of coilin reveals a common theme in nuclear body localization.

Molecular biology of the cell - 1 Dec 2000

Hebert M D, Matera A G

Abstract excerpt

We have found that coilin, the marker protein for Cajal bodies (coiled bodies, CBs), is a self-interacting protein, and we have mapped the domain responsible for this activity to the amino-terminus. Together with a nuclear localization signal, the self-interaction domain is necessary and sufficient for localization to CBs. Overexpression of various wild-type and mutant coilin constructs in HeLa cells results in...

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Identifiers

PMID: 11102515
DOI: 10.1091/mbc.11.12.4159
PMCID: PMC15064

Genes

PML

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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