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Article

Expression of involucrin in normal, hyperproliferative and neoplastic mouse keratinocytes

1 Dec 2000

Abstract excerpt

Involucrin is a protein precursor of the epidermal cornified envelope. Although expression of the human protein has been documented extensively, studies in the mouse have been hampered by a shortage of good antibodies. We describe the production of recombinant mouse involucrin and preparation of rabbit antisera to the protein that work well by immunohistochemistry and Western blotting. We confirm that in normal...

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PMID: 11099111
DOI: 10.1034/j.1600-0625.2000.009006431.x

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