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Article

The small proline-rich proteins constitute a multigene family of differentially regulated cornified cell envelope precursor proteins.

The Journal of investigative dermatology - 1 Jun 1995

Hohl D, de Viragh P A, Amiguet-Barras F, Gibbs S, Backendorf C, Huber M

Abstract excerpt

Loricrin, involucrin, small proline-rich protein (SPRR)1, SPRR2, and SPRR3 genes are located within a cluster of 1.5 Mbp on chromosome 1q21 and most likely evolved from a common ancestor. Monospecific polyclonal antibodies and cDNA probes were produced to investigate SPRR transcripts and proteins. SPRR expression was restricted to terminally differentiating squamous cells, preferentially located at the cell...

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Source

Identifiers

PMID: 7769256
DOI: 10.1111/1523-1747.ep12606176

Genes

SPRR3
LTB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The small proline-rich proteins constitute a multigene family of differentially regulated cornified cell envelope precursor proteins.PMID 7769256Read ↗

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