Article
The small proline-rich proteins constitute a multigene family of differentially regulated cornified cell envelope precursor proteins.
The Journal of investigative dermatology - 1 Jun 1995
Hohl D, de Viragh P A, Amiguet-Barras F, Gibbs S, Backendorf C, Huber M
Abstract excerpt
Loricrin, involucrin, small proline-rich protein (SPRR)1, SPRR2, and SPRR3 genes are located within a cluster of 1.5 Mbp on chromosome 1q21 and most likely evolved from a common ancestor. Monospecific polyclonal antibodies and cDNA probes were produced to investigate SPRR transcripts and proteins...
Topics
- Alleles
- Amino Acid Sequence
- Antibody Specificity
- Cornified Envelope Proline-Rich Proteins
- Humans
- Keratinocytes
- Membrane Proteins
- Molecular Sequence Data
- Polymorphism, Genetic
- Protein Precursors
- Proteins
- Transcription, Genetic
- Transglutaminases