Article
Epidermal growth factor receptor signaling activates orthodenticle expression during Drosophila head development.
DNA and cell biology - 1 Nov 2000
Amin A, Finkelstein R
Abstract excerpt
The relation between signal transduction pathways and the genes that specify regional identity remains poorly understood. We investigated the interaction between the epidermal growth factor receptor (EGFR) pathway and the homeobox gene orthodenticle (otd), which specifies cell fate during head development. Previous studies of head formation in Drosophila melanogaster demonstrated that reducing either EGFR...
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