Article
Cis-acting influences on Alu RNA levels.
Nucleic acids research - 1 Dec 2000
Alemán C, Roy-Engel A M, Shaikh T H, Deininger P L
Abstract excerpt
The human short interspersed repeated element (SINE), Alu, amplifies through a poorly understood RNA-mediated mechanism, termed retroposition. There are over one million copies of Alu per haploid human genome. The copies show some internal variations in sequence and are very heterogeneous in chromosomal environment. However, very few Alu elements actively amplify. The amplification rate has decreased greatly in...
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