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Article

Contribution of the multidrug efflux pump LfrA to innate mycobacterial drug resistance.

FEMS microbiology letters - 1 Dec 2000

Sander P, De Rossi E, Böddinghaus B, Cantoni R, Branzoni M, Böttger E C, Takiff H, Rodriquez R, Lopez G, Riccardi G

Abstract excerpt

Multidrug resistance (MDR) in bacteria has been associated with efflux pumps that export structurally unrelated compounds and decrease cytoplasmic drug accumulation. To investigate MDR in mycobacteria, we studied the Mycobacterium smegmatis mutant mc(2)11, which is resistant to doxorubicin, tetracycline, rhodamine, ethidium bromide and the hydrophilic fluoroquinolones. A genomic library constructed from this...

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PMID: 11094273
DOI: 10.1111/j.1574-6968.2000.tb09396.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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