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Article

Performance of Web tools for predicting changes in protein stability caused by mutations.

BMC bioinformatics - 5 Jul 2021

Marabotti Anna, Del Prete Eugenio, Scafuri Bernardina, Facchiano Angelo

Abstract excerpt

BACKGROUND: Despite decades on developing dedicated Web tools, it is still difficult to predict correctly the changes of the thermodynamic stability of proteins caused by mutations. Here, we assessed the reliability of five recently developed Web tools, in order to evaluate the progresses in the field. RESULTS: The results show that, although there are improvements in the field, the assessed predictors are still...

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Identifiers

PMID: 34225665
DOI: 10.1186/s12859-021-04238-w
PMCID: PMC8256537

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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