Article
Genetic interference in Trypanosoma brucei by heritable and inducible double-stranded RNA.
RNA (New York, N.Y.) - 1 Jul 2000
Shi H, Djikeng A, Mark T, Wirtz E, Tschudi C, Ullu E
Abstract excerpt
The use of double-stranded RNA (dsRNA) to disrupt gene expression has become a powerful method of achieving RNA interference (RNAi) in a wide variety of organisms. However, in Trypanosoma brucei this tool is restricted to transient interference, because the dsRNA is not stably maintained and its...
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