Article
Lung carcinoma-associated atypical adenomatoid hyperplasia, squamous cell dysplasia, and chromosome alterations in non-neoplastic bronchial mucosa.
Lung cancer (Amsterdam, Netherlands) - 1 Feb 2005
Kayser Klaus, Kosjerina Zdravko, Goldmann Torsten, Kayser Gian, Kazmierczak Bernd, Vollmer Ekkehard
Abstract excerpt
This article analyzes phenotype and genotype alterations of the lung in association with lung cancer. The frequency of phenotype preneoplastic lesions (atypical adenomatoid hyperplasia (AAH) and squamous cell dysplasia (SCD)) was analyzed at distinct distances from the tumor boundary in 150 lung carcinomas. AAH was noted in 19/150 (13%) cases and more frequently seen in adeno carcinomas, squamous cell dysplasia...
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