Mapping of the Region of Complement Receptor (CR) 1 Required for <i>Plasmodium falciparum</i> Rosetting and Demonstration of the Importance of CR1 in Rosetting in Field Isolates

Abstract excerpt

The malaria parasite Plasmodium falciparum induces a number of novel adhesion properties in the erythrocytes that it infects. One of these properties, the ability of infected erythrocytes to bind uninfected erythrocytes to form rosettes, is associated with severe malaria and may play a direct role in the pathogenesis of disease. Previous work has shown that erythrocytes deficient in complement receptor (CR) 1...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Complement system in diseases
• Share to Malaria Research and Control
• Share to Mosquito-borne diseases and control