Article
Plasma hydrogen peroxide production in human essential hypertension: role of heredity, gender, and ethnicity.
Hypertension (Dallas, Tex. : 1979) - 1 Nov 2000
Lacy F, Kailasam M T, O'Connor D T, Schmid-Schönbein G W, Parmer R J
Abstract excerpt
Oxygen free radicals, including hydrogen peroxide, may mediate oxidative stress in target organ tissues and contribute to cardiovascular complications in hypertension. To examine heritability of hydrogen peroxide production, we investigated this trait in a family-based cohort consisting of family members (n=236) ascertained through probands (n=57) with essential hypertension. Significant effects on hydrogen...
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