Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A mutational hot spot in the Prop-1 gene in Russian children with combined pituitary hormone deficiency.

Pituitary - 1 Apr 1998

Fofanova O V, Takamura N, Kinoshita E, Parks J S, Brown M R, Peterkova V A, Evgrafov O V, Goncharov N P, Bulatov A A, Dedov I I, Yamashita S

Abstract excerpt

Combined pituitary hormone deficiency (CPHD), including growth hormone (GH), prolactin (Prl) and thyroid-stimulating hormone (TSH) in children is now considered a heterogeneous syndrome. Recent findings on expression of mouse pituitary-specific homeodomain factors demonstrate dependence of adenopituitary ontogeny on interactive expression of these factors, suggesting their involvement in etiology of CPHD. Prophet...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes, Recessive
Share to Homeodomain Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Human Growth Hormone

Share to Pituitary Hormones

Share to Prolactin

Share to Russia

Share to Syndrome

Share to Thyrotropin

Source

Identifiers

PMID: 11081182
DOI: 10.1023/a:1009918924945

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A mutational hot spot in the Prop-1 gene in Russian children with combined pituitary hormone deficiency.PMID 11081182Read ↗

"Hot Spot" in the PROP1 Gene Responsible for Combined Pituitary Hormone DeficiencySemantic proximity Read ↗

"Hot spot" in the PROP1 gene responsible for combined pituitary hormone deficiency.Semantic proximity Read ↗

Familial combined pituitary hormone deficiency due to a novel mutation R99Q in the hot spot region of Prophet of Pit-1 presenting as constitutional growth delay.Semantic proximity Read ↗

Human Prop-1: cloning, mapping, genomic structure. Mutations in familial combined pituitary hormone deficiency.Semantic proximity Read ↗

A mutation in the POU-homeodomain of Pit-1 responsible for combined pituitary hormone deficiency.Semantic proximity Read ↗

Impaired Adrenocorticotropin-Adrenal Axis in Combined Pituitary Hormone Deficiency Caused by a Two-Base Pair Deletion (301–302delAG) in the Prophet of Pit-1 Gene<sup>1</sup>Semantic proximity Read ↗

Mutations Within the Transcription Factor PROP1 in a Cohort of Turkish Patients with Combined Pituitary Hormone DeficiencySemantic proximity Read ↗

Frequency of mutations in PROP-1 gene in Turkish children with combined pituitary hormone deficiency.Semantic proximity Read ↗

Characterization of Prophet of Pit-1 gene expression in normal pituitary and pituitary adenomas in humans.Semantic proximity Read ↗

[Genetic background of inherited multiple pituitary hormone deficiency. Mutations of PROP1 gene in Hungary].Semantic proximity Read ↗

Combined pituitary hormone deficiency in an inbred Brazilian kindred associated with a mutation in the PROP-1 gene.Semantic proximity Read ↗

Combined pituitary hormone deficiency: role of Pit-1 and Prop-1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.