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Article

IFN-gamma overexpression within the pancreas is not sufficient to rescue Pax4, Pax6, and Pdx-1 mutant mice from death.

Pancreas - 1 Nov 2000

Krakowski M, Yeung B, Abdelmalik R, Good A, Mocnik L, Sosa-Pineda B, St-Onge L, Gruss P, Sarvetnick N

Abstract excerpt

In the presence of interferon-gamma (IFN-gamma), pancreatic ductal epithelial cells grow continuously, and islets undergo neogenesis. To determine whether these new islets are derived from conventional precursors, we tested whether IFN-gamma can complement the loss of transcription factors known...

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Identifiers

PMID: 11075995
DOI: 10.1097/00006676-200011000-00011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11075995-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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