Article
Immortal human pancreatic duct epithelial cell lines with near normal genotype and phenotype.
The American journal of pathology - 1 Nov 2000
Ouyang H, Mou Lj, Luk C, Liu N, Karaskova J, Squire J, Tsao M S
Abstract excerpt
Immortal epithelial cell lines were previously established after transduction of the HPV16-E6E7 genes into primary cultures of normal pancreatic duct epithelial cells. Single clones were isolated that demonstrated near normal genotype and phenotype. The proliferation of HPDE6-E6E7c7 and c11 cells is anchorage-dependent, and they were nontumorigenic in SCID mice. The cell lines demonstrated many phenotypes of...
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