Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Wild-derived inbred mouse strains have short telomeres

15 Nov 2000

Abstract excerpt

Telomere length and telomerase activity directly affect the replicative capacity of primary human cells. Some have suggested that telomere length influences organismal lifespan. We compared telomere length distributions in a number of inbred and outbred established mouse strains with those of strains recently derived from wild mice. Telomere length was considerably shorter in wild-derived strains than in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetics, Aging, and Longevity in Model Organisms
Share to Telomeres, Telomerase, and Senescence

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 11071935
DOI: 10.1093/nar/28.22.4474

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Wild-derived inbred mouse strains have short telomeresPMID 11071935Read ↗

Mice with hyper-long telomeres show less metabolic aging and longer lifespansSemantic proximity Read ↗

Short telomeres are sufficient to cause the degenerative defects associated with aging.Semantic proximity Read ↗

Telomeres in the mouse have large inter-chromosomal variations in the number of T <sub>2</sub> AG <sub>3</sub> repeatsSemantic proximity Read ↗

Comparative biology of mammalian telomeres: hypotheses on ancestral states and the roles of telomeres in longevity determination.Semantic proximity Read ↗

Telomere dynamics in mice and humans.Semantic proximity Read ↗

The Rate of Increase of Short Telomeres Predicts Longevity in MammalsSemantic proximity Read ↗

Telomere length is inherited with resetting of the telomere set-point.Semantic proximity Read ↗

Long Telomeres Do Not Affect Cellular Fitness in Yeast.Semantic proximity Read ↗

Maximum life spans in mice are extended by wild strain alleles.Semantic proximity Read ↗

Why genes extending lifespan in model organisms have not been consistently associated with human longevity and what it means to translation researchSemantic proximity Read ↗

Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levelsSemantic proximity Read ↗

Developmental and tissue-specific regulation of mouse telomerase and telomere length.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.