Article
The SHR3 homologue from S. pombe demonstrates a conserved function of ER packaging chaperones.
Journal of cell science - 1 Dec 2000
Martínez P, Ljungdahl P O
Abstract excerpt
In Saccharomyces cerevisiae cells lacking SHR3, amino acid permeases do not enter into COPII transport vesicles and specifically accumulate in the membrane of the endoplasmic reticulum. Shr3p functions as a packaging chaperone to prime transport vesicle formation in the proximity of amino acid permeases. A genetic screen was developed that enabled the Schizosaccharomyces pombe SHR3 functional homologue,...
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