The SHR3 homologue from S. pombe demonstrates a conserved function of ER packaging chaperones.

doi:10.1242/jcs.113.23.4351

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

The SHR3 homologue from S. pombe demonstrates a conserved function of ER packaging chaperones.

Journal of cell science - 1 Dec 2000

Martínez P, Ljungdahl P O

Abstract excerpt

In Saccharomyces cerevisiae cells lacking SHR3, amino acid permeases do not enter into COPII transport vesicles and specifically accumulate in the membrane of the endoplasmic reticulum. Shr3p functions as a packaging chaperone to prime transport vesicle formation in the proximity of amino acid permeases. A genetic screen was developed that enabled the Schizosaccharomyces pombe SHR3 functional homologue,...

Topics

Alleles
Amino Acids
Base Sequence
COP-Coated Vesicles
Cloning, Molecular
DNA, Complementary
Endoplasmic Reticulum
Genes, Lethal
Membrane Proteins
Molecular Chaperones
Molecular Sequence Data
Mutagenesis
Phenotype
Plasmids
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Schizosaccharomyces
Schizosaccharomyces pombe Proteins

Source

Open in PubMed

Identifiers

PMID: 11069779
DOI: 10.1242/jcs.113.23.4351

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics