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Article

Altered secretion of a TIGR/MYOC mutant lacking the olfactomedin domain.

Biochimica et biophysica acta - 15 Nov 2000

Caballero M, Rowlette L L, Borrás T

Abstract excerpt

TIGR/MYOC, a novel 504 amino acids (aa) protein of unknown function, has recently been linked to glaucoma. The protein is both intra- and extracellular and most known mutations map to its C-terminus, an olfactomedin-like domain. To investigate the properties of a TIGR/MYOC peptide lacking this important domain, we constructed a replication-deficient adenovirus with the first 344 aa and over-expressed the...

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Source

Identifiers

PMID: 11068187
DOI: 10.1016/s0925-4439(00)00068-5

Genes

MYOC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Altered secretion of a TIGR/MYOC mutant lacking the olfactomedin domain.PMID 11068187Read ↗

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