Article
Antibody regulation of B cell development.
Nature immunology - 1 Nov 2000
Meffre E, Casellas R, Nussenzweig M C
Abstract excerpt
Antibodies on the surface of B lymphocytes trigger adaptive immune responses and control a series of antigen-independent checkpoints during B cell development. These physiologic processes are regulated by a complex of membrane immunoglobulin and two signal transducing proteins known as Ig alpha and Ig beta. Here we focus on the role of antibodies in governing the maturation of B cells from early...
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