Article
Genetic therapy for pain management.
Current review of pain - 1 Jan 2000
Wilson S P, Yeomans D C
Abstract excerpt
Two approaches to genetic therapy for the management of chronic pain have recently been investigated in animal models of pain. First, transgene-mediated delivery of antinociceptive molecules to the cerebrospinal fluid has been performed with engineered cell lines transplanted to the subarachnoid space and with recombinant adenoviruses that transduce pia mater cells. Second, the phenotype of nociceptive neurons...
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