Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Apparent founder effect during the early years of the San Francisco HIV type 1 epidemic (1978-1979).

AIDS research and human retroviruses - 10 Oct 2000

Foley B, Pan H, Buchbinder S, Delwart E L

Abstract excerpt

HIV-1 envelope sequence variants were RT-PCR amplified from serum samples cryopreserved in San Francisco in 1978-1979. The HIV-1 subtype B env V3-V5 sequences from four homosexual men clustered phylogenetically, with a median nucleotide distance of 2.8%, reflecting a recent common origin. These early U.S. HIV-1 env variants mapped close to the phylogenetic root of the subtype B tree while env variants collected...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AIDS Vaccines
Share to DNA, Viral
Share to Drug Design

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Envelope Protein gp120

Share to HIV Infections

Share to Peptide Fragments

Share to San Francisco

Source

Identifiers

PMID: 11054259
DOI: 10.1089/088922200750005985

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Apparent founder effect during the early years of the San Francisco HIV type 1 epidemic (1978-1979).PMID 11054259Read ↗

Key Positions of HIV-1 Env and Signatures of Vaccine Efficacy Show Gradual Reduction of Population Founder Effects at the Clade and Regional Levels.Semantic proximity Read ↗

The epidemic origin and molecular properties of B': a founder strain of the HIV-1 transmission in Asia.Semantic proximity Read ↗

U.S. Human Immunodeficiency Virus Type 1 Epidemic: Date of Origin, Population History, and Characterization of Early StrainsSemantic proximity Read ↗

Sexually-transmitted/founder HIV-1 cannot be directly predicted from plasma or PBMC-derived viral quasispecies in the transmitting partner.Semantic proximity Read ↗

Development of an HIV-1 reference panel of subtype B envelope clones isolated from the plasma of recently infected individuals.Semantic proximity Read ↗

Diversity of the human immunodeficiency virus type 1 envelope glycoprotein in San Francisco Men's Health Study participants.Semantic proximity Read ↗

Minimization of genetic distances by the consensus, ancestral, and center-of-tree (COT) sequences for HIV-1 variants within an infected individual and the design of reagents to test immune reactivity.Semantic proximity Read ↗

High incidence of unusual cysteine variants in gp120 envelope proteins from early HIV type 1 infections from a Phase 3 vaccine efficacy trial.Semantic proximity Read ↗

The number and genetic relatedness of transmitted/founder virus impact clinical outcome in vaginal R5 SHIVSF162P3N infection.Semantic proximity Read ↗

Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes.Semantic proximity Read ↗

Genomic Structure of an Attenuated Quasi Species of HIV-1 from a Blood Transfusion Donor and RecipientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.