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Article

Diagnostic utility of fluorescence <i>in situ</i> hybridization in mantle‐cell lymphoma

1 Sept 2000

Abstract excerpt

Mantle-cell lymphoma (MCL) has a poorer prognosis than other small B-cell lymphomas, thus a definitive diagnosis is essential. The t(11;14)(q13;q32) associated with MCL juxtaposes portions of CCND1 (11q13) and IGH (14q32), resulting in over-expression of cyclin D1. In this study, a highly sensitive two-colour fluorescence in situ hybridization (FISH) method was developed to detect t(11;14)(q13;q32) in nuclei...

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Identifiers

PMID: 11054068
DOI: 10.1046/j.1365-2141.2000.02303.x

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Diagnostic utility of fluorescence <i>in situ</i> hybridization in mantle‐cell lymphomaPMID 11054068Read ↗

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