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Article

Subcellular localization of presenilins during mouse preimplantation development.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Nov 2000

Jeong S J, Kim H S, Chang K A, Geum D H, Park C H, Seo J H, Rah J C, Lee J H, Choi S H, Lee S G, Kim K, Suh Y H

Abstract excerpt

The genes defective in familial Alzheimer's disease encode the proteins presenilin 1 and 2 (PS1 and 2). Expression of presenilins (PSs) and their proteolytic processing are regulated during neuronal development. Even though these proteins are detected and regulated mainly in Golgi and endoplasmic reticulum, their subcellular distribution during the development is not known. The present study aimed to investigate...

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PMID: 11053237
DOI: 10.1096/fj.99-1068com

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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