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Article

A Transcriptional Regulator of a Pristinamycin Resistance Gene in Streptomyces coelicolor

1 Jan 2001

Abstract excerpt

Pip is a pristinamycin-induced transcriptional regulator protein detected in many Streptomyces species by its ability to specifically bind sequence motifs within the promoter of a Streptomyces pristinaespiralis multidrug resistance gene (ptr). To investigate the possible role of Pip in regulating multidrug resistance, it was purified from a genetically characterized species, Streptomyces coelicolor, utilizing an...

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PMID: 11050092
DOI: 10.1074/jbc.m007690200

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