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Establishment of a Rescue System for Canine Distemper Virus

15 Nov 2000

Abstract excerpt

Canine distemper virus (CDV) has been rescued from a full-length cDNA clone. Besides Measles virus (MV) and Rinderpest virus, a third morbillivirus is now available for genetic analysis using reverse genetics. A plasmid p(+)CDV was constructed by sequential cloning using the Onderstepoort vaccine strain large-plaque-forming variant. The presence of a T7 promoter allowed transcription of full-length antigenomic...

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PMID: 11044118
DOI: 10.1128/jvi.74.22.10737-10744.2000

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