Article
Cloning, localisation and functional expression of a novel human, cerebellum specific, two pore domain potassium channel.
Brain research. Molecular brain research - 20 Oct 2000
Chapman C G, Meadows H J, Godden R J, Campbell D A, Duckworth M, Kelsell R E, Murdock P R, Randall A D, Rennie G I, Gloger I S
Abstract excerpt
We have isolated, by degenerate PCR, a complementary DNA encoding a novel two pore domain potassium channel. This is the 7th functional member of the human tandem pore domain potassium channel family to be reported. It has an open reading frame of 1.125 kb and encodes a 374 amino acid protein which shows 62% identity to the human TASK-1 gene: identity to other human members of the family is 31-35% at the amino...
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