Article
Mycobacterium leprae typing by genomic diversity and global distribution of genotypes.
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association - 1 Jun 2000
Matsuoka M, Maeda S, Kai M, Nakata N, Chae G T, Gillis T P, Kobayashi K, Izumi S, Kashiwabara Y
Abstract excerpt
The genetic diversity and related global distribution of 51 Mycobacterium leprae isolates were studied. Isolates were obtained from leprosy patients from 12 geographically distinct regions of the world and two were obtained from nonhuman sources. Polymerase chain reaction (PCR) followed by DNA sequencing was performed targeting the rpoT gene of M. leprae. Isolates were classified into two groups based on the...
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