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Article

Geographically distinct isolates of Mycobacterium leprae exhibit no genotypic diversity by restriction fragment-length polymorphism analysis.

Molecular microbiology - 1 Oct 1990

Williams D L, Gillis T P, Portaels F

Abstract excerpt

Differentiation of microorganisms for taxonomic purposes is based primarily on phenotypic characteristics, which are the direct or cumulative result of gene expression. Since expression of phenotypic characteristics usually relies on in vitro growth of a microorganism, non-cultivable organisms, such as Mycobacterium leprae, present major problems for the identification of potential variants based on phenotypic...

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PMID: 1981802
DOI: 10.1111/j.1365-2958.1990.tb00542.x

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