Article
Genetic diversity of mycobacterium leprae isolates from Brazilian leprosy patients.
Leprosy review - 1 Sept 2009
Fontes Amanda Nogueira Brum, Sakamuri Rama Murthy, Baptista Ida Maria Foschiani Dias, Ura Somei, Moraes Milton Ozório, Martínez Alejandra Nóbrega, Sarno Euzenir Nunes, Brennan Patrick J, Vissa Varalakshmi D, Suffys Philip Noel
Abstract excerpt
INTRODUCTION: Leprosy is a chronic disease caused by infection with Mycobacterium leprae, an obligate intracellular parasite. A problem in studying the transmission of leprosy is the small amount of variation in bacterial genomic DNA. The discovery of variable number of tandem repeats (VNTRs) allowed the detection of strain variation in areas with a high prevalence of leprosy. Four genotypes of M. leprae based on...
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