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SNP genotypes of Mycobacterium leprae isolates in Thailand and their combination with rpoT and TTC genotyping for analysis of leprosy distribution and transmission.

Japanese journal of infectious diseases - 1 Jan 2012

Phetsuksiri Benjawan, Srisungngam Sopa, Rudeeaneksin Janisara, Bunchoo Supranee, Lukebua Atchariya, Wongtrungkapun Ruch, Paitoon Soontara, Sakamuri Rama Murthy, Brennan Patrick J, Vissa Varalakshmi

Abstract excerpt

Based on the discovery of three single nucleotide polymorphisms (SNPs) in Mycobacterium leprae, it has been previously reported that there are four major SNP types associated with different geographic regions around the world. Another typing system for global differentiation of M. leprae is the analysis of the variable number of short tandem repeats within the rpoT gene. To expand the analysis of geographic...

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PMID: 22274158

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