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Article

Rapid variable-number tandem-repeat genotyping for Mycobacterium leprae clinical specimens.

Journal of clinical microbiology - 1 Jun 2009

Kimura Miyako, Sakamuri Rama Murthy, Groathouse Nathan A, Rivoire Becky L, Gingrich David, Krueger-Koplin Susan, Cho Sang-Nae, Brennan Patrick J, Vissa Varalakshmi

Abstract excerpt

Mycobacterium leprae is the noncultivable pathogen of leprosy. Since the genome sequence of an isolate of M. leprae has become available, multiple-locus variable-number tandem-repeat (VNTR) analysis (MLVA) has been explored as a tool for strain typing and identification of chains of transmission of leprosy. In order to discover VNTRs and develop methods transferable to clinical samples, MLVA was applied to a...

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Identifiers

PMID: 19386839
DOI: 10.1128/JCM.02019-08
PMCID: PMC2691099

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