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Article

Genetic predisposition and somatic diversification in tumor development and progression.

Advances in cancer research - 1 Jan 2001

Shibata D, Aaltonen L A

Abstract excerpt

Studies on human cancer predisposition syndromes have contributed significantly to our understanding on tumor initiation and progression. Work performed on hereditary colon cancer has been particularly fruitful. Much of the molecular background of the various intestinal polyposis syndromes, such as familial adenomatous polyposis (FAP), juvenile polyposis, and Peutz-Jeghers syndrome, has been revealed, pinpointing...

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PMID: 11034541
DOI: 10.1016/s0065-230x(01)80013-0

Genes

FAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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