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Article

Modulation of Oxidant Stress In Vivo in Chronic Cigarette Smokers

1 Jul 1996

Abstract excerpt

BACKGROUND: Free radical-induced oxidative damage is thought to be involved in the pathogenesis of diseases associated with cigarette smoking. We examined the production of 8-epi-prostaglandin (PG) F2 alpha, a stable product of lipid peroxidation in vivo, and its modulation by aspirin and antioxidant vitamins in chronic cigarette smokers. METHODS AND RESULTS: We performed the following studies: (1) a...

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PMID: 8964113
DOI: 10.1161/01.cir.94.1.19

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