Article
Lipid peroxidation as determined by plasma isoprostanes is related to disease severity in mild asthma.
Lipids - 1 Sept 2000
Wood L G, Fitzgerald D A, Gibson P G, Cooper D M, Garg M L
Abstract excerpt
Oxidlative stress is believed to play an important role in the pathophysiology of asthma. Recently discovered F2-isoprostanes, of which 8-iso-PGF2alpha is the most well-known isomer, have emerged as the most reliable marker of in vivo oxidative stress. The aim of this study was to examine 8-iso-PGF2alpha as a biomarker of oxidative stress in mild asthma in relation to endogenous and dietary antioxidant...
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