Article
Interleukin-6 promoter polymorphism is associated with bone quality assessed by calcaneus ultrasound and previous fractures in a cohort of 75-year-old women.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Oct 2004
Nordström Anna, Gerdhem Paul, Brändström Helena, Stiger Fredrik, Lerner Ulf H, Lorentzon Mattias, Obrant Karl, Nordström Peter, Akesson Kristina
Abstract excerpt
Interleukin 6 (IL-6) is a multifunctional cytokine and a potent stimulator of bone resorption and has been implicated in the pathogenesis of osteoporosis in postmenopausal women. The aim of this study was to investigate if a functional IL-6 promoter polymorphism (-174) was related to bone mass and fractures in a cohort consisting of 964 postmenopausal Caucasian women aged 75 years. Bone mineral density (BMD;...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.