Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dietary restriction during murine development provides protection against MNU-induced mutations.

Mutation research - 31 Oct 2000

Shima N, Swiger R R, Heddle J A

Abstract excerpt

The developmental stage is the most rapid period for the accumulation of somatic mutations. Epidemiological studies have also suggested a significant role of early life for cancer susceptibility, showing a protective effect of modest dietary restriction early in life. To determine if mutation rate, diet, and cancer risk are related, we have investigated the effect of dietary restriction on somatic mutations early...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Primers
Share to Energy Intake
Share to Feeding Behavior

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Litter Size

Share to Methylnitrosourea

Share to Neoplasms, Experimental

Share to Pregnancy

Share to Viral Proteins

Source

Identifiers

PMID: 11027974
DOI: 10.1016/s1383-5718(00)00104-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dietary restriction during murine development provides protection against MNU-induced mutations.PMID 11027974Read ↗

The effect of dietary restriction during development in utero on the frequency of spontaneous somatic mutations.Semantic proximity Read ↗

A carcinogenic western diet does not induce somatic mutations in various target tissues of transgenic C56BL/6 mice.Semantic proximity Read ↗

No change in spontaneous mutation frequency or specificity in dietary restricted mice.Semantic proximity Read ↗

Differential mutation of transgenic and endogenous loci in vivo.Semantic proximity Read ↗

Effects of calorie restriction on the age-dependent accumulation of mutations in the small intestine of lacZ-transgenic mice.Semantic proximity Read ↗

The effects of methyl-donor deficiency on mutation induction and transgenerational instability in mice.Semantic proximity Read ↗

Frequency and spectrum of ENU-induced mutation in the Phi X174 transgene in mouse splenic lymphocytes and their significance to spontaneous transgenic rodent mutation frequencies.Semantic proximity Read ↗

Spontaneous mutation during fetal development and post-natal growth.Semantic proximity Read ↗

Spontaneous mutations in digestive tract of old mice show tissue-specific patterns of genomic instability.Semantic proximity Read ↗

Raising gestational choline intake alters gene expression in DMBA‐evoked mammary tumors and prolongs survivalSemantic proximity Read ↗

Effect of Maternal and Post-Weaning Folate Supply on Gene-Specific DNA Methylation in the Small Intestine of Weaning and Adult Apc+/Min and Wild Type MiceSemantic proximity Read ↗

Effect of dietary supplementation on the frequency of spontaneous lacZ mutations in the developing colon.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.